TRACE, our improved method for identifying TF binding sites through DNase footprinting, has been published in Genome Research. TRACE combines chromatin accessibility profiles with DNA sequence motifs to infer quantitative transcription factor occupancy across the genome. The approach improves footprinting by explicitly modeling both the local accessibility signal and the sequence preferences of each factor. Congratulations to Ningxin on leading this work!
Our manuscript on DNase footprinting is published in Genome Research!
People
Boyle Lab members
More from the lab
